Is there a way in which you can induce segregation chromosome 21 at early stages to control down syndrome

Question: Is there a way in which you can induce segregation chromosome 21 at early stages to control down syndrome
- Keywords:
  chromosome,
  downsyndrome
Asked by 242pink33 to Silvia on 23 May 2018.
- Silvia Situma answered on 23 May 2018:
  
  Conventionally Downs syndrome has been deemed irremediable. However recently some researchers have aimed to develop ‘chromosome therapy’ for Downs Syndrome.
  This has been done by:
  1) inserting a TK-NEO marker that can be selected against in order to eliminate one copy of chromosome 21
  2) inactivating one of the copies of chromosome 21 by inserting into it a copy of the XIST gene that normally inactivates one of the two X chromosomes in female cells.
  Even though these procedures have provided proof of principle, they have not been applied to due to their requirement of elaborate and cumbersome multi-step genetic engineering.

Question: Is there a way in which you can induce segregation chromosome 21 at early stages to control down syndrome